Children born to mothers with active eating disorders during pregnancy demonstrated an elevated risk for developing ADHD and autism spectrum disorders, according to a Swedish population-based cohort study published in JAMA Network Open. “In addition to the direct effect on the fetal growth and development, the intrauterine environment presumably influences health during childhood and throughout life. Precise mechanisms and interactions are poorly defined, but it is assumed that intrauterine environmental exposures, including nutritional factors, affect neurodevelopment and immune maturation,” Ängla Mantel, MD, PhD, of the division of clinical epidemiology at Karolinska University Hospital in Stockholm, Sweden, and colleagues wrote. “Thus, hypothetically, children of mothers with eating disorders might be prone to develop specific conditions, including neurodevelopmental disorders.” |