“recent Nutrients study examines the relationship iron deficiency (ID) and sleep-related disorders.
Iron and sleep/wake disorders
Iron is a trace element present in neurons, astrocytes, oligodendrocytes, and microglia. Iron is also an essential component for both the synthesis of neurotransmitters that regulate the sleep/wake cycle, as well as the dopamine synthesis pathway.
These observations indicate that ID could significantly influence sleep and wake patterns; however, iron levels are rarely considered in the clinical management of sleep/wake disorders.
The most frequent causes of sleep/wake disorders are hyper-arousability, restless leg syndrome (RLS), hyper-motor restlessness, restless sleep disorder (RSD), and periodic limb movements in sleep (PLMS).”